Jean-Yves Scoazec Selected Research

Carcinogenesis

1/2022	Cancer Induces a Stress Ileopathy Depending on β-Adrenergic Receptors and Promoting Dysbiosis that Contributes to Carcinogenesis.
5/2017	Hepatocyte nuclear factor 1α suppresses steatosis-associated liver cancer by inhibiting PPARγ transcription.
10/2014	Regulation of YAP by mTOR and autophagy reveals a therapeutic target of tuberous sclerosis complex.
2/2012	PPARγ contributes to PKM2 and HK2 expression in fatty liver.
1/2012	GNAS-activating mutations define a rare subgroup of inflammatory liver tumors characterized by STAT3 activation.
5/2010	Cooperation between the thyroid hormone receptor TRalpha1 and the WNT pathway in the induction of intestinal tumorigenesis.
7/2009	Inactivation of TIF1gamma cooperates with Kras to induce cystic tumors of the pancreas.
10/2008	In colon carcinogenesis, the cytoskeletal protein gelsolin is down-regulated during the transition from adenoma to carcinoma.
10/2008	NF-kappaB regulates netrin-1 expression and affects the conditional tumor suppressive activity of the netrin-1 receptors.
4/2008	Clonal expansion of mutated mitochondrial DNA is associated with tumor formation and complex I deficiency in the benign renal oncocytoma.

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Jean-Yves Scoazec Research Topics

Disease

131	Neoplasms (Cancer) 04/2024 - 02/2002
18	Neoplasm Metastasis (Metastasis) 04/2021 - 08/2002
16	Hepatocellular Carcinoma (Hepatoma) 01/2022 - 08/2002
16	Neuroendocrine Tumors (Neuroendocrine Tumor) 11/2019 - 06/2009
12	Carcinogenesis 01/2022 - 09/2004
11	Carcinoma (Carcinomatosis) 11/2023 - 10/2003
11	Infections 10/2022 - 05/2002
11	Fibrosis (Cirrhosis) 01/2022 - 04/2002
10	Neuroendocrine Carcinoma 01/2023 - 08/2009
10	Adenocarcinoma 02/2010 - 09/2002
9	Adenoma (Adenomas) 04/2014 - 08/2003
8	Melanoma (Melanoma, Malignant) 06/2022 - 01/2015
8	Hepatitis 09/2017 - 03/2002
7	Colonic Neoplasms (Colon Cancer) 04/2021 - 11/2007
7	Hepatitis C 08/2014 - 09/2003
6	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 10/2023 - 01/2016
6	Colorectal Neoplasms (Colorectal Cancer) 12/2011 - 04/2003
5	Liver Diseases (Liver Disease) 11/2023 - 07/2007
5	Disease Progression 01/2023 - 10/2003
5	Squamous Cell Carcinoma of Head and Neck 01/2019 - 01/2016
5	Hypoxia (Hypoxemia) 01/2018 - 05/2002
4	Tertiary Lymphoid Structures 04/2024 - 01/2019
4	Non-alcoholic Fatty Liver Disease 11/2023 - 03/2010
4	Head and Neck Neoplasms (Head and Neck Cancer) 01/2021 - 01/2017
4	Carcinoid Tumor (Carcinoid) 01/2021 - 01/2011
4	Hyperplasia 04/2020 - 02/2003
4	Liver Cell Adenoma (Hepatocellular Adenoma) 01/2017 - 03/2006
4	Inflammation (Inflammations) 10/2009 - 09/2006
3	Biliary Tract Neoplasms (Biliary Tract Cancer) 01/2024 - 12/2017
3	Fatty Liver 11/2023 - 03/2010
3	Prostatic Neoplasms (Prostate Cancer) 11/2023 - 01/2020
3	Lung Neoplasms (Lung Cancer) 10/2023 - 12/2016
3	Sarcoma (Soft Tissue Sarcoma) 01/2023 - 01/2017
3	Hypertension (High Blood Pressure) 01/2019 - 10/2009
3	Primitive Neuroectodermal Tumors (PNET) 01/2018 - 10/2015
3	Liver Neoplasms (Liver Cancer) 05/2017 - 07/2004
3	Hemorrhage 01/2017 - 02/2006
3	Alcoholic Liver Diseases (Alcoholic Liver Disease) 01/2016 - 05/2007
3	Alcoholic Liver Cirrhosis (Alcoholic Cirrhosis) 08/2015 - 05/2007
3	Pancreatic Neoplasms (Pancreatic Cancer) 08/2012 - 07/2009

Drug/Important Bio-Agent (IBA)

17	Biomarkers (Surrogate Marker)IBA 01/2023 - 03/2004
14	Proteins (Proteins, Gene)FDA Link 10/2023 - 09/2004
11	Immune Checkpoint InhibitorsIBA 04/2024 - 10/2017
10	LigandsIBA 10/2023 - 08/2002
9	Netrin-1IBA 08/2012 - 04/2003
8	RNA (Ribonucleic Acid)IBA 12/2023 - 01/2017
7	DNA (Deoxyribonucleic Acid)IBA 01/2024 - 08/2003
7	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 12/2014 - 10/2003
6	PlatinumIBA 01/2023 - 01/2017
6	Chromogranin AIBA 01/2021 - 12/2005
6	Cisplatin (Platino)FDA LinkGeneric 01/2019 - 08/2006
5	AntibodiesIBA 12/2023 - 02/2014
5	Somatostatin (Somatotropin Release-Inhibiting Factor)IBA 10/2021 - 01/2009
5	Oxaliplatin (Eloxatin)FDA LinkGeneric 01/2021 - 08/2009
5	Messenger RNA (mRNA)IBA 01/2020 - 07/2007
5	Imatinib Mesylate (Gleevec)FDA Link 01/2018 - 10/2004
5	SynaptophysinIBA 01/2017 - 02/2003
4	Etoposide (VP 16)FDA LinkGeneric 01/2023 - 01/2018
4	Fluorouracil (Carac)FDA LinkGeneric 01/2023 - 08/2006
4	CateninsIBA 01/2022 - 04/2012
4	Temozolomide (Temodar)FDA LinkGeneric 06/2019 - 06/2012
4	Cetuximab (Erbitux)FDA Link 01/2019 - 01/2016
4	MTOR InhibitorsIBA 01/2018 - 01/2010
4	Everolimus FDA Link 01/2018 - 06/2008
4	Dihydrotachysterol (AT 10)IBA 01/2018 - 02/2007
4	Adrenal Cortex Hormones (Corticosteroids)IBA 09/2017 - 06/2006
4	Gemcitabine FDA Link 10/2015 - 08/2006
4	LipidsIBA 09/2015 - 12/2012
4	IntegrinsIBA 01/2015 - 08/2002
4	Antiviral Agents (Antivirals)IBA 08/2014 - 04/2004
3	Bevacizumab (Avastin)FDA Link 01/2023 - 02/2012
3	Phosphotransferases (Kinase)IBA 01/2023 - 02/2012
3	AntigensIBA 01/2023 - 07/2004
3	Transcription Factors (Transcription Factor)IBA 12/2022 - 02/2012
3	Anaplastic Lymphoma KinaseIBA 01/2022 - 12/2016
3	B7-H1 AntigenIBA 01/2022 - 01/2016
3	InterferonsIBA 01/2022 - 05/2004
3	Hormones (Hormone)IBA 04/2021 - 12/2005
3	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 11/2020 - 12/2019
3	Tyrosine Kinase InhibitorsIBA 01/2020 - 12/2008
3	Streptozocin (Streptozotocin)FDA Link 01/2018 - 08/2009
3	Hepatocyte Nuclear FactorsIBA 05/2017 - 03/2007
3	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 08/2011 - 12/2006
3	AflatoxinsIBA 04/2011 - 06/2004
3	Octreotide (Sandostatin)FDA LinkGeneric 01/2011 - 01/2009
3	EnzymesIBA 01/2010 - 12/2006
3	beta CateninIBA 03/2006 - 09/2003
3	Ribavirin (Virazole)FDA LinkGeneric 05/2004 - 08/2002
2	Androgen Receptors (Androgen Receptor)IBA 11/2023 - 10/2023
2	enzalutamideIBA 11/2023 - 01/2020
2	HLA Antigens (Human Leukocyte Antigens)IBA 01/2023 - 01/2023

Therapy/Procedure

37	Therapeutics 04/2024 - 10/2003
28	Liver Transplantation 11/2023 - 04/2002
22	Drug Therapy (Chemotherapy) 01/2023 - 03/2003
10	Immunotherapy 04/2024 - 06/2016
8	Radiotherapy 01/2021 - 08/2006
7	Precision Medicine 01/2023 - 12/2017
3	Castration 11/2023 - 01/2020
3	Chemoradiotherapy 01/2018 - 01/2016
3	Pancreatectomy 02/2010 - 08/2003